Temporomandibular Disorder Comorbidity
AbstractTemporomandibular disorders (TMD) are conceptualized as a group of diverse conditions related to the jaw muscles, temporomandibular joint (TMJ) and related tissues and may be associated with...
View ArticleAssessing Cutaneous Sensory Function and Vasomotor Responses
AbstractCutaneous sensory function can be assessed under different conditions such as physiological, pathological and following certain treatments. Quantitative sensory testing (QST) includes a battery...
View ArticleThe association of headache frequency with pain interference and the burden...
AbstractBackgroundA better understanding of potential relationship between mood disorders, sleep quality, pain, and headache frequency may assist clinicians in determining optimal therapeutic programs....
View ArticleIdentification of subgroups of patients with tension type headache with...
AbstractBackgroundIdentification of subgroups of patients with different levels of sensitization and clinical features can help to identify groups at risk and the development of better therapeutic...
View ArticleThe burden of headache is associated to pain interference, depression and...
AbstractBackgroundTo investigate variables associated at one year (longitudinal design) with the physical or emotional component of burden in chronic tension type headache (CTTH).MethodsOne hundred and...
View ArticleThe time course of brief and prolonged topical 8% capsaicin-induced...
AbstractTopically applied high-concentration capsaicin induces reversible dermo-epidermal denervation and depletion of capsaicin-sensitive nociceptors. This causes desensitization of distinct sensory...
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Knee joint vibroarthrography of asymptomatic subjects during loaded...
AbstractVibroarthrography (VAG) has been proposed as a diagnostic tool for knee joint disorders. The methodological aspects of VAG assessments, such as sensor placement and outcomes measures have not...
View ArticlePreferential activation of small cutaneous fibers through small pin electrode...
AbstractBackgroundElectrical stimulation is widely used in experimental pain research but it lacks selectivity towards small nociceptive fibers. When using standard surface patch electrodes and...
View ArticleIntensive, personalized multimodal rehabilitation in patients with primary or...
AbstractBackgroundRecent evidence has shown that many patients suffer from persistent pain and impaired function after primary or revision total knee arthroplasty (TKA). Post-surgical complications may...
View ArticleVariables associated with use of symptomatic medication during a headache...
AbstractBackgroundPharmacological treatment of patients with tension-type headache (TTH) includes symptomatic (acute) and prophylactic (preventive) medication. No previous study has investigated...
View ArticleNeuromuscular exercise and pain neuroscience education compared with pain...
AbstractBackgroundTotal knee arthroplasty (TKA) is considered an effective treatment for pain relief and improved physical performances in end-stage knee osteoarthritis. However, several studies have...
View ArticleAssociation of dynamic and widespread mechanical sensitivity in cluster headache
AbstractWe investigated if dynamic pressure pain sensitivity in the symptomatic area is associated with pressure sensitivity in local and distant pain-free areas in cluster headache (CH). A pressure...
View ArticleSensory defunctionalization induced by 8% topical capsaicin treatment in a...
AbstractSubpopulations of primary nociceptors (C- and Aδ-fibers), express the TRPV1 receptor for heat and capsaicin. During cutaneous inflammation, these afferents may become sensitized, leading to...
View ArticleA mechanism-based proof of concept study on the effects of duloxetine in...
AbstractBackgroundThe global burden of osteoarthritis (OA) is steadily increasing due to demographic and lifestyle changes. The nervous system can undergo peripheral and central neuroplastic changes...
View ArticleUnderstanding the interaction between clinical, emotional and psychophysical...
AbstractObjectiveEvidence supports that tension-type headache (TTH) involves complex underlying mechanisms. The current study aimed to quantify potential multivariate relationships between...
View ArticleSafety of Intravenous and Inhalation Anesthetics
AbstractHere is presented, in chronological order, the studies that established the standards and determined the parameters currently considered for the safe use of anesthetic agents administered by...
View ArticleProfiling migraine patients according to clinical and psychophysical...
AbstractAimsInvestigate if different clinical and psychophysical bedside tools can differentiate between district migraine phenotypes in ictal/perictal (cohort 1) and interictal (cohort 2)...
View ArticleTrigeminocervical pain sensitivity during the migraine cycle depends on...
AbstractObjectiveThis experimental study aimed to assess pain sensitivity in low-frequency episodic migraine (LFEM), high-frequency episodic migraine (HFEM), and chronic migraine (CM) patients across...
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